False positives and false negatives do occur. In a clinical study, 13% of patients without colorectal cancer or advanced adenomas received a positive result (false positive) and 8% of patients with cancer received a negative result (false negative). https://www.cologuardhcp.com/faq !3% false positive and 8% false negative seems kinda shitty. Ah, ha ha ha ha ha ! ! ! I crack me up. P.S. https://www.gastroconsa.com/how-cologuard-tests-may-end-up-costing-you-thousands/